Analysis of the Quality of Life and Perceived Benefits by the Elderly Inserted in the Public Sports and Leisure Policies of the Municipality of Canoas/RS
Coordinator:
Patrick da Silveira Gonçalves
Email:
patrick.goncalves@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
This research project seeks to analyze the health-related quality of life and the benefits perceived by the elderly who attend sports and leisure programs offered by the municipal government of Canoas/RS. The research will follow a mixed approach, applying the WHOQOL-Bref questionnaire, consisting of closed questions and a questionnaire with open questions prepared by the researcher. The sample will be 233 elderly people who attend sports and leisure programs offered by the municipal government of Canoas/RS.
Analysis of the Quality of Life and Perceived Benefits by the Elderly Inserted in the Public Sports and Leisure Policies of the Municipality of Canoas/RS
Analyzing Experiential and Interventive Learning in the Work Health Education Program (PET-Saúde)
Coordinator:
Lidiane Isabel Filippin
Email:
lidiane.filippin@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
Secretaria Municipal da Saúde - Porto Alegre Bolsa
The main objective of the PET-Health: Equity program is to provide education activities through work in the health area, with the purpose of strengthening the integration between education, health services, and the community. The program aims to contribute to the training of future health professionals, in addition to promoting the creation and expansion of the conditions necessary to value current and future workers in the SUS context. Health equity is fundamental to ensure that everyone, especially the workers at the Emergency Hospital of Porto Alegre - RS, have access to fair working conditions in health services, regardless of their employment, socioeconomic, or geographical situation. This aspect is particularly relevant in a diverse country such as Brazil, where regional differences can have a significant impact on the health of populations. In this sense, the present project seeks to understand the interventional experiences in the Occupational Health Education Program (PET-Saúde) and to analyze the health and work conditions of female health workers in a general hospital in Rio Grande do Sul. This is an exploratory study, with a quanti-qualitative approach, with SUS workers. Finally, the study is expected to provide detailed insights into the PET-Saúde experience, highlighting both strengths and areas to be improved.
Analyzing Experiential and Interventive Learning in the Work Health Education Program (PET-Saúde)
Artificial Intelligence and Photobiomodulation for Diabetic Foot Ulcers
Coordinator:
Rodrigo Della Méa Plentz
Email:
rodrigo.plentz@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
HTM INDUSTRIA DE EQUIPAMENTOS ELETRO-ELETRONICOS LTDA - (Inovações e novas tecnologias em Fisioterapia e Reabilitação)
Diabetic foot ulcer (UPD) is a public health problem. Given the impact of UPD on patients and the health system, initiatives with artificial intelligence (AI) have been developed for the automated detection of these injuries. Among adjuvant therapies, photobiomodulation has stood out as a potential treatment modality to accelerate ulcer healing. The objectives of the present study are to validate an AI model for the evaluation of diabetic foot ulcers and to investigate the effects of photobiomodulation on the healing of diabetic foot ulcers. To this end, this project will be developed in three phases. Phase 1 of the study is characterized by a cross-sectional study. Patients' ulcers will be evaluated using the AI model and compared to the clinician's assessment. Phase 2 is characterized by a systematic review of randomized clinical trials to verify the effect of photobiomodulation therapy and different doses on diabetic foot ulcers. Phase 3 of the study is characterized by a randomized clinical trial that will be conducted according to the findings of phase 1 and 2. Patients will be randomized into two groups, one group will receive the photobiomodulation protocol with the ideal dose for treating diabetic foot ulcers and the other will receive placebo photobiomodulation. If phase 1 demonstrates that the accuracy of the injury assessment performed by the AI is very similar to the clinician's assessment, this will be used as an assessment tool in the clinical trial.
Artificial Intelligence and Photobiomodulation for Diabetic Foot Ulcers
Connection with Nature and Ecological Behavior in Basic Education School Environments in Brazil
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
The Connection with Nature (CN), which designates a subjective link, can lead to ecological care. Although some defend this bond as innate, it is a consensus that it must be promoted from childhood, since contact with natural environments promotes it, provides health benefits, and stimulates ecological behaviors (EC) of protection and care for nature. Studies show that NC is an important predictor of EC, however, there is much to be understood about its possibilities, especially in the childhood and adolescence of those living in urban centers. In fact, there is increasing disconnection and detachment from nature by the inhabitants of urban centers, which impacts both their health and the preservation of natural areas. This scenario is especially compelling in Brazil, whose exuberance of nature and the symbolic values of this relationship are under threat. Based on studies that indicate that most families and schools find it difficult to provide children and adolescents with nature more frequent encounters, which further reduces the opportunity for this subjective bond to emerge, this study aims to investigate the opportunities for interaction with nature offered to students by Brazilian basic education schools. Thus, it is intended: to survey the outdoor/natural spaces of schools in some cities located in all geographical regions of the country (Brasilia-DF; Canoas-RS; Ribeirão Preto-SP; Natal-RN; Manaus-AM; Boa Vista-RR); to find out what managers/teachers think about the inclusion of nature in pedagogical practice; and to investigate how students relate to nature and its respective CE. It is expected to provide a portrait of this school-nature scenario in Brazil and to contribute to public policies aimed at the inclusion of nature-based activities to encourage activities in outdoor and green areas in schools, and also to collaborate with the planning and reformulation of the school environment for the presence of green areas in its spaces.
Connection with Nature and Ecological Behavior in Basic Education School Environments in Brazil
Efficiency in reducing color, turbidity, and eco-/cyto-/geno-toxicity of azo dyes by means of a biosorbent derived from grape seed
Coordinator:
Fernanda Rabaioli da Silva
Email:
fernanda.silva@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
PGQP Edital Fapergs 09/2023
Dyes have been used in human history for many centuries and are of great importance in various economic sectors. There are several classes of dyes, with azoic dyes being the most used commercially. These dyes, however, represent an environmental challenge because they are discarded in large quantities in bodies of water, causing contamination. When reduced, they can generate aromatic amines, which are mutagenic and carcinogenic substances. Different techniques for removing these contaminants have been studied, including biological, physical, and chemical processes. Among the emerging technologies, advanced oxidative processes have shown promise. However, adsorption is one of the most effective techniques for removing dyes from wastewater, especially using biosorbent materials. Among them, grape pomace should be highlighted, which has a lignocellulosic nature, that is, structural components such as cellulose, hemicellulose and lignin, which give it characteristics that enhance its potential as an adsorbent. One way to test dye removal efficiency is to make use of physical, chemical, and biological tests. Thus, the general objective of this project is to investigate the potential of grape seed as a biosorbent in the removal of azo dyes and its efficiency in reducing cytotoxic, genotoxic and ecotoxic effects in different biological models: (a) in vivo, through the analysis of raw and treated samples containing azodorants in Daphnia magna and (b) in vitro, through cytotoxicity and genotoxicity tests in the HepG2 cell line and mutagenicity in the Ames Test. It is expected to achieve a greater understanding of the efficiency of the biosorbent produced from grape seed in the treatment of azodors with regard, mainly, to the reduction of color, turbidity and toxicity.
Efficiency in reducing color, turbidity, and eco-/cyto-/geno-toxicity of azo dyes by means of a biosorbent derived from grape seed
Floods and extreme rains in Rio Grande do Sul: assessment of psychosocial, genotoxic and zoonotic risks in impacted environments
Coordinator:
Fernanda Rabaioli da Silva
Email:
fernanda.silva@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
FAPERGS - Auxílio financeiro
This project aims to investigate the effects of extreme rains and floods in affected regions of Rio Grande do Sul, more specifically in Canoas, adopting an integrated and multidisciplinary approach that combines environmental, human and animal health. The research evaluates ecotoxicological, psychosocial, cellular, molecular and zoonotic impacts through the analysis of biomonitors, biomarkers and questionnaires, with the purpose of identifying harm to health and environmental quality. Among the main objectives, the mapping of water and soil quality, the analysis of genotoxicity and toxicity in humans and animals, and the investigation of mental disorders, such as depression and post-traumatic stress disorder, stand out. The study also examines the consequences for animal health, focusing on zoonoses. Based on the results obtained, mitigation and intervention strategies will be developed, aimed at improving environmental and community resilience in the face of natural disasters. This study promises a significant contribution to public health and environmental science, providing essential data for the formulation of effective public policies and disaster management practices.
Floods and extreme rains in Rio Grande do Sul: assessment of psychosocial, genotoxic and zoonotic risks in impacted environments
Gender bias in the management of chest pain
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
Cardiovascular diseases stand out as the main causes of death in both genders, with coronary artery disease assuming a significant proportion in this scenario. Globally, coronary artery disease accounts for 15 and 20 of all deaths in women and men, respectively. It is interesting to note that the prevalence of cardiovascular disease is lower in premenopausal women and that the onset of the disease occurs later in them, in addition to having more atypical symptoms. In addition to these differences in relation to the characteristics observed in men, there is evidence that, regardless of age, women with coronary artery disease have worse outcomes. Some explanations are given by the fact that women are older when an ischemic event occurs and have more comorbidities. Presenting with atypical symptoms may also contribute, resulting in erroneous or late diagnoses. One concern, however, is that this scenario of unfavorable outcomes is, in part, because women receive lower quality health care, a phenomenon known as gender disparity. This disparity is linked to the belief that cardiovascular diseases almost exclusively affect men, something that is reflected in the perception of both patients and doctors. Gender bias is defined as unintentional systematic discrimination against women or men. Gender bias in the diagnosis and treatment of cardiovascular disease has been reported in some studies but not in others. The objective of this study is to verify whether there is a difference in relation to sex in the management and outcomes of patients treated in the emergency room for chest pain. This is a prospective cohort study that will be conducted at the Institute of Cardiology - University Foundation of Cardiology (IC-FUC) in Porto Alegre. Patients over 18 years of age who seek emergency services at the hospital with non-traumatic chest pain as their main complaint will be included in the study. The primary outcome will be hospital admission. Secondary outcomes will be risk classification, troponin request, electrocardiogram, and ICU admission rate.
Gender bias in the management of chest pain
Genotoxicological Analysis of Different Environmental Agents and Complex Mixtures: Health Effect
Coordinator:
Juliana da Silva
Email:
juliana.silva@unilasalle.edu.br
Research Line:
Line 2 - Pathological Processes
Promotion:
CNPq Research Productivity Scholarship - Level 2
Muitos químicos potencialmente danosos, tanto naturais como de origem antropogênica, são eliminados no ambiente constantemente. Tem crescido muito o interesse em se biomonitorar e biomarcar ecossistemas terrestres e aquáticos quanto à exposição a agentes danosos, bem como o efeito destes sobre a saúde humana e a relação com diferentes doenças. Monitorar os tipos e as quantidades de tóxicos que estão constantemente entrando em contato com o ambiente e com o ser humano é uma tarefa exaustiva. Apesar dos inúmeros métodos analíticos disponíveis, alguns dos quais serão utilizados neste projeto, coletar amostras suficientes em tempo hábil, continua sendo um grande obstáculo na avaliação de danos ambientais, seja ao ecossistema como um todo, ou de forma específica, como ao ser humano. O monitoramento ambiental, principalmente no que diz respeito a organismos expostos a poluentes (biomonitores), utilizando sistemas testes biológicos (biomarcadores), propicia uma promissora ferramenta para a identificação de poluentes capazes de causar dano à saúde humana e ao ambiente. Além disto, quanto à avaliação de produtos naturais e sintéticos, estudos que buscam informações referentes ao efeito danoso ao DNA causado por estes que são utilizados para fins medicinais são relevantes em termos de esclarecimento de mecanismos de ação das suas substâncias, e desta forma para seu uso de forma segura. Assim, é objetivo geral deste projeto avaliar a genotoxicidade de diferentes compostos presentes em compostos sintéticos e naturais, além de identificar poluentes capazes de afetar a saúde ambiental e humana. Para tanto, são utilizados diferentes bioensaios in vitro e in vivo: Teste de micronúcleos, ensaio cometa e tamanho telomérico. Estas metodologias são empregadas para avaliar: a atividade mutagênica de fármacos, extratos vegetais e compostos presentes na dieta alimentar humana (avaliação de produtos naturais e sintéticos); a toxicidade genética associada a poluentes atmosféricos (incluindo solo) e aquáticos (biomonitoramento ambiental); avaliação da saúde humana em relação à exposição ambiental e ocupacional; instabilidade genômica e a relação com diferentes doenças. Desta forma, espera-se integrar de forma interdisciplinar diferentes projetos relacionados à saúde humana e ambiental em busca da compreensão dos processos de saúde e doença e suas implicações no desenvolvimento humano. Neste sentido busca-se a prevenção primária, a qual engloba ações realizadas para evitar a ocorrência da doença, sendo as estratégias voltadas para a redução da exposição aos fatores de risco.
Genotoxicological Analysis of Different Environmental Agents and Complex Mixtures: Health Effect
Immunoinformatics Platform for the Design of Effective and Personalized Vaccine Experiments
Coordinator:
Gustavo Fioravanti Vieira
Email:
gustavo.vieira@unilasalle.edu.br
Research Line:
Line 2 - Pathological Processes
Promotion:
Bolsista de Produtividade em Pesquisa do CNPq - Nível 2
Immunoinformatics is a specific area of bioinformatics and computational biology that deals specifically with immunological phenomena. In this specific project, the focus is on events involving the recognition of infected cells by CD8+ T cells (cytotoxic T lymphocytes). The approach involves everything from investigating the steps involved in the antigen processing pathway to the interaction between the T-cell receptor (TCR) and the complexed epitope of the MHC molecule, which defines the outcome of the triggering of an immune response or not. For this purpose, different tools are used to predict each of these stages. In addition to the use of tools that are scientifically established, is it also planned to develop tools within the project based on a structural analysis of the different ones? Bottlenecks? (proteosome cleavage, MHC binding, etc.). Regarding the prediction of the immunogenicity of an epitope, the project contemplates the large scale analysis of viral infection targets and tumors already described in the literature. Based on this comparison, it is expected to define structural patterns that are the fingerprints of these diseases. Structural databases and molecular modeling tools will be employed in this process, as well as statistical clustering methods to extract the shared patterns. The result of this pipeline will allow us to infer a set of T cell targets in a new emerging viral infection or a tumor from a specific tissue, for example.
Immunoinformatics Platform for the Design of Effective and Personalized Vaccine Experiments
Impact of COVID-19 Infections on Morbimortality
Coordinator:
Márcio Manozzo Boniatti
Email:
marcio.boniatti@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
The research project emerged as a response to the global COVID-19 pandemic, seeking to understand and mitigate the devastating effects of the disease on critically ill patients. This multifaceted project will cover a wide range of epidemiological, clinical, and translational studies, aimed at elucidating the main factors that influence morbidity and mortality in this vulnerable population group. The researchers involved will use an integrated approach that combines clinical and laboratory data analysis to map the critical determinants of the outcome of critically ill patients infected with SARS-CoV-2. In addition, the project will seek to identify prognostic biomarkers and specific risk factors that can help to stratify patients and direct more effective therapeutic interventions. The results of this project are expected to provide information to optimize the screening, early diagnosis, and management of critically ill patients with COVID-19, with the ultimate goal of reducing the morbidity and mortality associated with the disease.
Impact of COVID-19 Infections on Morbimortality
Investigation of the cytotoxicity and genotoxicity of Roundup Transorb in glioblastoma cell lines
Coordinator:
Fernanda Rabaioli da Silva
Email:
fernanda.silva@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
Bolsista de Produtividade em Pesquisa do CNPq - Nível 2
Glyphosate is a broad-spectrum herbicide used on major agricultural crops, such as soybeans, for example. It is characterized by being persistent in soils and surface and groundwater, contaminating the environment. Human contamination, on the other hand, can occur through occupational, food, or environmental means. Populations chronically and acutely exposed to agrochemicals may suffer health impairment with the manifestation of neurodegenerative diseases. Additionally, glyphosate is cited by the International Agency for Research on Cancer as a probable human carcinogen. Among the various glyphosate formulations used in Rio Grande do Sul (RS, Brazil), the one with the commercial name Roundup Transorb (RT) stands out. Previous studies demonstrated synergistic toxicity in glyphosate-based formulations. Considering the complex health issue of glyphosate, including DNA damage, neurotoxicity and cancer, this study aims to evaluate the cytotoxicity and genotoxicity of RT in two glioblastoma cell lines: U87 (proficient for p53) and U251 (mutant for p53; genetic alteration related to the early development of head cancer), as well as to survey the main proteins involved in exposure to glyphosate in the nervous system, using Systems Biology. For data mining, bioinformatics tools such as STRING 11.0 and STITCH 5.0 will be used, which will serve as the basis for the design of binary networks in the Cytoscape 3.6.0 program. For the analysis of this model, the Molecular Complex Detection (MCODE), the Biological Network Gene Ontology (BinGO) and CentiScape programs will be applied. Thus, it is worth noting that these evaluations will be important to understand the action of RT on nervous system cells, contributing to the understanding of the possible effects on human exposure.
Investigation of the cytotoxicity and genotoxicity of Roundup Transorb in glioblastoma cell lines
Pathological Diagnosis of Zoonoses of Public Health Importance Affecting Domestic Animals
Coordinator:
Daniele Mariath Bassuino Konradt
Email:
daniele.konradt@unilasalle.edu.br
Research Line:
Line 2 - Pathological Processes
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
Zoonoses are infectious diseases transmitted from animals to humans. From the obvious need to interconnect studies and research involving human, animal and environmental health, the concept of Single Health emerged through international organizations. This project aims to detect, describe and diagnose regional zoonoses affecting domestic animals through pathological findings and the use of complementary techniques. Initially, the team will contact partner veterinary doctors to treat, collect and send samples of animals suspected of dying from a zoonosis to a Veterinary Pathology laboratory for histological processing. The hematoxylin and eosin stained slides will be sent to the project team for analysis and description of the cases. Starting in 2025, these samples must be sent to the Unilasalle Veterinary Pathology Laboratory, and new partners must be signed with the region's veterinarians to send samples to the University. For all cases, a report will be generated that includes the basic information of each case, as well as the macro and microscopic findings observed and the final diagnosis. In addition, a photographic record of necropsy and microscopic lesions will be recorded. When necessary, samples may be collected and submitted for complementary tests according to the clinical-pathological suspicion to partner laboratories. After the completion of the cases, a moment will be held to discuss the followed up cases, evaluating the diagnoses, epidemiological findings, observed risk factors and the contact population. At the end of the project, the objective is the compilation of data, the publication of technical and scientific material, and the return to the affected community with accessible information about the identified etiological agent, transmission mechanisms, and methods of control and prophylaxis for each disease.
Pathological Diagnosis of Zoonoses of Public Health Importance Affecting Domestic Animals
Performance of biosorbents produced from grape fillet and their application in viticulture effluent treatment
Coordinator:
Fernanda Rabaioli da Silva
Email:
fernanda.silva@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
Edital recém contratado - ARC Fapergs
Brazilian viticulture has attracted attention in various segments of the economy, because the country, in addition to being a major producer of grains such as soybeans and corn, stands out in the cultivation of grapes. Due to this growth, a volume of by-products (bark, bagasse and bagasse) has been generated, making it crucial to implement technological solutions for the use of this waste in the generation of products with greater added value. The recovery of fibers and bioactive compounds from grape fillet enables the development of biosorbents for the agro-industrial sector. Thus, this project aims to find alternatives for the viticulture sector, minimizing environmental and economic impact, protecting the environment and increasing profitability in this segment. To this end, adsorption tests aimed at evaluating the efficiency of the use of grape filament in the treatment of viticulture effluent will be carried out. In addition, physico-chemical tests and ecotoxicological tests. Finally, the results found will be analyzed and compared with the conventional treatment already performed by the company.
Performance of biosorbents produced from grape fillet and their application in viticulture effluent treatment
Predicting the Risk of Rheumatoid Sarcopenia through Artificial Intelligence: A Methodological Study
Coordinator:
Lidiane Isabel Filippin
Email:
lidiane.filippin@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
Sarcopenia is a generalized skeletal muscle disorder characterized by a reduction in muscle mass and muscle strength, which in turn is associated with poor physical performance [1]. In the general population, this condition is associated with an increased likelihood of adverse outcomes, such as falls, fractures, hospitalizations, and death [2]. Factors such as aging, unhealthy lifestyle, and chronic inflammatory diseases are associated with sarcopenia [2]. Although the term sarcopenia was initially proposed as age-related muscle loss, it has now been used more generally as a skeletal muscle disease applicable at various ages and multiple clinical settings, including rheumatoid arthritis (RA), where it describes the decline in muscle mass and function regardless of age [3,4]. Patients with RA, a chronic systemic inflammatory disease of the synovial joints [5], often have changes in body composition and physical function [6]. In addition, RA patients often have a decrease in muscle mass, particularly in the appendicular skeletal muscle, while they generally have normal or increased fat mass [7,8]. Additionally, muscle strength is typically lower when compared to healthy individuals [6]. Recently, a review described these negative effects of RA on skeletal muscle as rheumatoid sarcopenia [9]. Therefore, there is no universal agreement on the definitions for this condition, causing confusion among scientists, doctors, and health professionals about what definitions, cutoff points, and muscle assessment tools to employ. On the other hand, a systematic review with meta-analysis reported that the prevalence of sarcopenia in RA patients ranges from 24 to 30 [10]. Although the prevalence of sarcopenia in patients with RA was explored in previous cross-sectional studies using varied approaches, few used the revised definition of the European Working Group on Sarcopenia in the Elderly (EWGSOP2) and none defined the risk factors for sarcopenia in patients with rheumatoid arthritis. Although there are uncertainties about the most effective method for evaluating sarcopenia, due to its multifactorial nature, it is widely recognized that sarcopenia associated with RA is highly prevalent among patients with this condition. In addition, rheumatoid sarcopenia represents a significant clinical challenge, considerably compromising patients' functionality and increasing the risk of falls and mortality.
Predicting the Risk of Rheumatoid Sarcopenia through Artificial Intelligence: A Methodological Study
Promoting Mental Health and Quality of Life Throughout the Life Cycle
Coordinator:
Aline Groff Vivian
Email:
aline.vivian@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
A infância, adolescência e adultez emergente são fases do ciclo da vida em que ocorrem importantes transformações socioemocionais, cognitivas, biológicas e comportamentais. Na infância, torna-se fundamental identificar fatores de risco e proteção que têm sido associados a condições adversas, a fim de promover a saúde mental da criança e prevenir o surgimento de agravos na adolescência e vida adulta. Já na adolescência surgem novas demandas de desenvolvimento que podem causar conflitos de relacionamento, preocupações com a saúde e a própria identidade dentre outros, que podem repercutir posteriormente na qualidade de vida do jovem e do adulto. Alguns desses aspectos, seguem sendo pauta de desenvolvimento na adultez emergente. Nesse sentido, o objetivo deste estudo será investigar os fatores de risco e proteção à saúde mental na infância, adolescência e adultez bem como suas repercussões na qualidade de vida. Especificamente, buscar-se-á analisar a percepção dos genitores quanto à saúde mental de seus filhos; compreender quais os indicadores de risco para as crianças e adolescentes ao longo da vida, bem como descrever as impressões dos adolescentes quanto à saúde mental e qualidade de vida. Por fim, será analisada a qualidade de vida de adultos emergentes, bem como suas impressões acerca da própria saúde mental. Trata-se de um estudo transversal, exploratório e descritivo. Participarão desse estudo 75 genitores com filhos cursando o ensino fundamental I e 45 alunos do ensino fundamental II e ensino médio, de escolas públicas da Região Metropolitana de Porto Alegre/RS e 30 adultos jovens universitários (n=150). As entrevistas semiestruturadas serão gravadas e transcritas, submetidas à análise de conteúdo qualitativa de Bardin, com o auxílio do software MaxQda. Os adolescentes e jovens adultos responderão também a uma ficha de dados sociodemográficos, bem como ao instrumento WoqolBref cujos dados serão submetidos à análise estatística. Os resultados serão organizados em categorias derivadas dos achados, analisados à luz da literatura sobre o tema. Considera-se que compreender fatores de risco e proteção à saúde mental ao longo da vida pode contribuir para o planejamento de ações promotoras da saúde nesse contexto, desde a infância e adolescência, bem como repercutir na qualidade de vida na vida adulta. Além disso, espera-se que a partir dos resultados se possa gerar produtos técnicos como cartilhas, e-books, dentre outros, para subsidiar intervenções que poderão ser realizadas tanto em contexto escolar como no âmbito privado da comunidade. Palavras-chave: infância, adolescência, adultez, promoção da saúde mental, qualidade de vida.
Promoting Mental Health and Quality of Life Throughout the Life Cycle
Search for non-coding RNAs as new epigenetic biomarkers of chronic microvascular complications of diabetes mellitus
Coordinator:
Cristine Dieter
Email:
cristine.dieter@unilasalle.edu.br
Research Line:
Line 2 - Pathological Processes
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
Identify changes in the expression of non-coding RNAs (miRNAs, lncRNAs, and circRNAs) in microvascular complications of DM in patients with DM1.
Search for non-coding RNAs as new epigenetic biomarkers of chronic microvascular complications of diabetes mellitus
Verify characteristics associated with complications and cardiovascular responses in procedures performed on critically ill patients
Coordinator:
Márcio Manozzo Boniatti
Email:
marcio.boniatti@unilasalle.edu.br
Research Line:
Line 1 - Health Assessment and Promotion
Promotion:
SOCIEDADE PORVIR CIENTIFICO - (Programa Unilasalle de Pesquisa)
It is a multidisciplinary project that aims to expand the understanding of cardiovascular conditions, in addition to including the study of other common scenarios in critically ill patients. This project will cover a variety of studies, from epidemiological analyses to clinical studies, with the objective of identifying risk factors, predictors, and outcomes related mainly to cardiovascular complications in critical settings. The researchers involved will use an integrated approach, combining clinical data, biomarkers and imaging tests to investigate the complex interactions between critical conditions and cardiovascular performance, in addition to other systems. The results of this project are expected to contribute significantly to the advancement of knowledge about cardiovascular implications in critically ill patients, providing a solid basis for more effective preventive and therapeutic interventions.
Verify characteristics associated with complications and cardiovascular responses in procedures performed on critically ill patients